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Journal Articles Frontiers in Microbiology Year : 2019

Editorial: Horizontal Gene Transfer Mediated Bacterial Antibiotic Resistance

Abstract

Four sequence type 664 (ST664) (serotype O:5) strains of Pseudomonas aeruginosa that were highly resistant to antibiotics, including ceftolozane-tazobactam and ceftazidime-avibactam, but were susceptible to colistin were found to harbor the gene encoding the rare class C β-lactamase PAC-1 on a chromosomally located Tn 1721 -like transposon. The bla PAC-1 gene was associated with the 16S rRNA methylase determinant rmtF2 , which confers pan-aminoglycoside resistance.

Dates and versions

hal-03505272 , version 1 (30-12-2021)

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Katy Jeannot, Dongchang Sun, Yonghong Xiao, Charles Knapp. Editorial: Horizontal Gene Transfer Mediated Bacterial Antibiotic Resistance. Frontiers in Microbiology, 2019, 10 (12), pp.19168-19177. ⟨10.3389/fmicb.2019.01933⟩. ⟨hal-03505272⟩

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