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Article Dans Une Revue Antimicrobial Agents and Chemotherapy Année : 2019

Acquisition of Class C β-Lactamase PAC-1 by Sequence Type 644 Strains of Pseudomonas aeruginosa

Résumé

Four sequence type 664 (ST664) (serotype O:5) strains of Pseudomonas aeruginosa that were highly resistant to antibiotics, including ceftolozane-tazobactam and ceftazidime-avibactam, but were susceptible to colistin were found to harbor the gene encoding the rare class C β-lactamase PAC-1 on a chromosomally located Tn 1721 -like transposon. The bla PAC-1 gene was associated with the 16S rRNA methylase determinant rmtF2 , which confers pan-aminoglycoside resistance.

Dates et versions

hal-04225913 , version 1 (03-10-2023)

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Citer

Maxime Bour, Damien Fournier, Thomas Jové, Armelle Pouzol, Guillaume Miltgen, et al.. Acquisition of Class C β-Lactamase PAC-1 by Sequence Type 644 Strains of Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 2019, 63 (12), pp.1469-1472. ⟨10.1128/AAC.01375-19⟩. ⟨hal-04225913⟩
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