Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation - Archive ouverte HAL Access content directly
Journal Articles Nanoscale Year : 2018

Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation

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Abstract

This study emphasizes the interest to set up relevant in vitro models using human hepatic cells to evaluate the hepatotoxicity of nanomedicines.
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hal-03666681 , version 1 (12-05-2022)

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Raphaël Cornu, Nathalie Rougier, Yann Pellequer, Alf Lamprecht, Paul Hamon, et al.. Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation. Nanoscale, 2018, 10 (11), pp.5171-5181. ⟨10.1039/c8nr00226f⟩. ⟨hal-03666681⟩

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