Efficacy of transcranial direct current stimulation in reducing impulsivity in borderline personality disorder (TIMBER): study protocol of a randomized controlled clinical trial - Archive ouverte HAL Access content directly
Journal Articles Trials Year : 2019

Efficacy of transcranial direct current stimulation in reducing impulsivity in borderline personality disorder (TIMBER): study protocol of a randomized controlled clinical trial

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Julie Giustiniani
Coralie Joucla
  • Function : Author
Djamila Bennabi
  • Function : Author
Magali Nicolier
Thibault Chabin
Caroline Masse
  • Function : Author
Benoît Trojak
  • Function : Author
Pierre Vandel
  • Function : Author
  • PersonId : 910812
Emmanuel Haffen
  • Function : Author
Damien Gabriel
  • Function : Author

Abstract

The aim of the present study was to investigate the relationship between trait impulsivity, risk-taking, and decision-making performance. We recruited 20 healthy participants who performed the Iowa Gambling Task (IGT) and the Balloon Analog Risk Task (BART) to measure decision-making and risk-taking. The impulsivity was measured by the Barratt Impulsiveness Scale. Resting-state neural activity was recorded to explore whether brain oscillatory rhythms provide important information about the dispositional trait of impulsivity. We found a significant correlation between the ability to develop a successful strategy and the propensity to take more risks in the first trials of the BART. Risk-taking was negatively correlated with cognitive impulsivity in participants who were unable to develop a successful strategy. Neither risk-taking nor decision-making was correlated with cortical asymmetry. In a more exploratory approach, the group was sub-divided in function of participants’ performances at the IGT. We found that the group who developed a successful strategy at the IGT was more prone to risk, whereas the group who failed showed a greater cognitive impulsivity. These results emphasize the need for individuals to explore their environment to develop a successful strategy in uncertain situations, which may not be possible without taking risks.

Dates and versions

hal-03656186 , version 1 (01-05-2022)

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Julie Giustiniani, Coralie Joucla, Djamila Bennabi, Magali Nicolier, Thibault Chabin, et al.. Efficacy of transcranial direct current stimulation in reducing impulsivity in borderline personality disorder (TIMBER): study protocol of a randomized controlled clinical trial. Trials, 2019, 20 (1), pp.347. ⟨10.1186/s13063-019-3427-z⟩. ⟨hal-03656186⟩

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