Cognitive Impairment Involving Social Cognition in SPG4 Hereditary Spastic Paraplegia - Université de Franche-Comté Accéder directement au contenu
Article Dans Une Revue Behavioural Neurology Année : 2016

Cognitive Impairment Involving Social Cognition in SPG4 Hereditary Spastic Paraplegia

Cognitive Impairment Involving Social Cognition in SPG4 Hereditary Spastic Paraplegia.

Ludivine Chamard
  • Fonction : Auteur
Sabrina Ferreira
  • Fonction : Auteur
Alexa Pijoff
  • Fonction : Auteur
Manon Silvestre
  • Fonction : Auteur
Eric Berger
  • Fonction : Auteur
Eloi Magnin

Résumé

Objectives . To describe cognitive assessment including social cognition in SPG4 patients. Methods . We reported a series of nine patients with SPG4 mutation with an extensive neuropsychological examination including social cognition assessment. Results . None of our patients presented with mental retardation or dementia. All presented with mild cognitive impairment with a high frequency of attention deficit (100%), executive disorders (89%), and social cognition impairment (78%). An asymptomatic patient for motor skills presented with the same cognitive profile. No correlation was found in this small sample between cognitive impairment and motor impairment, age at disease onset, or disease duration. Conclusions . SPG4 phenotypes share some cognitive features of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Cognitive disorders including executive disorders and social cognition impairment are frequent in SPG4 patients and might sometimes occur before motor disorders. Therefore, cognitive functions including social cognition should be systematically assessed in order to improve the clinical management of this population.

Dates et versions

hal-03630202 , version 1 (04-04-2022)

Identifiants

Citer

Ludivine Chamard, Sabrina Ferreira, Alexa Pijoff, Manon Silvestre, Eric Berger, et al.. Cognitive Impairment Involving Social Cognition in SPG4 Hereditary Spastic Paraplegia. Behavioural Neurology, 2016, 2016, pp.1-6. ⟨10.1155/2016/6423461⟩. ⟨hal-03630202⟩

Collections

UNIV-FCOMTE
18 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More